GlobalWSday
  • Home
  • About WS
  • For Clinicians
    • Endocrinologists
    • Ophthalmologists
    • Consider Wolfram Syndrome
    • Wolfram Syndrome Clinical Guidelines
    • ER Stress Disorders/Diabetes Requisition
  • Treatment
    • Treatment Strategies
    • Treatment Pipeline
    • Wolfram Syndrome Clinical Guidelines
  • For Patients
  • Donate
  • Contact
  • More Information
    • Connect to WS Research
    • WS Patient Registries

Treatment of
​Wolfram syndrome

Treatment Strategie​s

Stop Progression of the Disease
Current research strategies include the use of - 
  • Chemical chaperones/molecular prosthetics
  • ER calcium stabilizers 
  • ER stress reducers
Repair Damaged Tissue
Regenerative treatments
  • AAV delivery
  • Repurposed drugs that result in proliferation
  • iPSC cell replacement
​Correct the Gene Defect
Gene therapy 
  • CRISPR cas9
  • AAV WT WFS1 rescue
Picture

Wolfram Syndrome Clinical Guidelines

Picture
 Implementation and planning headed by WSUK 
Picture
with support from
Picture
Picture
Picture
Picture
Picture
Picture
Wolfram Syndrome Germany
Picture
Proudly powered by Weebly
  • Home
  • About WS
  • For Clinicians
    • Endocrinologists
    • Ophthalmologists
    • Consider Wolfram Syndrome
    • Wolfram Syndrome Clinical Guidelines
    • ER Stress Disorders/Diabetes Requisition
  • Treatment
    • Treatment Strategies
    • Treatment Pipeline
    • Wolfram Syndrome Clinical Guidelines
  • For Patients
  • Donate
  • Contact
  • More Information
    • Connect to WS Research
    • WS Patient Registries